
🔥 TRENDING · SOLD 13× IN LAST 30 DAYS
Focus · Neuroplasticity · Mood
Spurs growth of neural connections
The Stamets Stack — Lions Mane mushroom, Psilocybe cubensis, and Niacin working synergistically to support neuroplasticity, mood, and cognitive function.
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ABOUT THIS FORMULA
Lions Brain is our best-selling formula — a precise implementation of the Stamets Stack that has taken the mycology and wellness world by storm. This synergistic trio works together to support the growth of new neural connections, enhance cognitive function, and stabilize mood.
Lions Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF), supporting the repair and growth of neurons. Combined with a microdose of Psilocybe cubensis to amplify neuroplasticity, and Niacin (Vitamin B3) to drive the compounds deeper into the nervous system via the flush response.
Hand-crafted using organic and wild-crafted mushrooms. No fillers, no binders — just pure plant medicine in a vegan capsule.
THE STAMETS STACK
Developed by mycologist Paul Stamets, the Stamets Stack is the most researched microdosing protocol in the world — combining three synergistic compounds to rewire the brain from the inside out.

CAPSULES · BEST SELLER
Lions Mane · Psilocybe cubensis · Niacin
25 capsules — 3–5×/week protocol
$72.22

LIQUID EXTRACT
Dual-extracted · Full-spectrum
Faster absorption · 2 oz dropper
$66.66
Lions Mane stimulates NGF production — a protein essential for the growth, maintenance, and survival of neurons. NGF literally rebuilds your brain.
The microdose of Psilocybe cubensis activates 5-HT2A receptors, dramatically amplifying neuroplasticity and making the brain more receptive to Lions Mane's NGF.
Niacin (Vitamin B3) causes a peripheral flush that drives the active compounds deeper into the nervous system — reaching areas that would otherwise be inaccessible.
Users report reduced anxiety, lifted depression, and greater emotional resilience. The stack supports serotonin pathways and default mode network regulation.
Improved memory, sharper focus, and faster processing. Studies show Lions Mane can reverse cognitive decline and support recovery from neurological damage.
Mycologist Paul Stamets — the world's leading mushroom researcher — developed this protocol after decades of research. He holds a patent on the combination.
"The combination of Lion's Mane, psilocybin, and niacin creates a synergistic effect that is greater than the sum of its parts — potentially offering a pathway to enhanced neurogenesis and cognitive repair."
— PAUL STAMETS, MYCOLOGIST & RESEARCHER
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