PEGANUM HARMALA
Potentiate · Activate · Deepen
Dual Extraction · 2 oz
This handcrafted extract of Peganum harmala (Syrian rue) is a traditional potentiator revered for its MAO-inhibiting and psychoactive properties. Carefully crafted using a dual-extraction process with organic cane alcohol, organic glycerin, and spring water, this formulation preserves a broad spectrum of active alkaloids and delivers them in a bioavailable format.
Key Compounds
The seeds of Peganum harmala are rich in harmala alkaloids, primarily harmine, harmaline, and tetrahydroharmine—beta-carbolines also found in Banisteriopsis caapi, the vine of the Amazonian brew ayahuasca. These compounds act as reversible MAO-A inhibitors (RIMAs), allowing for the oral activity of certain otherwise-inactive compounds like DMT and enhancing the effects of entheogens such as psilocybin, mescaline, and 5-MeO-DMT.
Other naturally occurring alkaloids include:
Harmalol
Harmane
Harmidine
Norharmine
Tetrahydroharmaline
Scientific Insight
Studies have shown that harmala alkaloids:
Inhibit monoamine oxidase A (MAO-A), affecting neurotransmitter metabolism such as serotonin, dopamine, and melatonin
Exhibit neuroprotective and antioxidant properties (Mol Pharmacol. 2008)
May support mood regulation and induce altered states of consciousness when combined with other plant sacraments
(Note: This is not a recreational product. This extract is offered as a spiritual and ceremonial preparation aid.)
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