PEGANUM HARMALA
Potentiate · Activate · Deepen

Dual Extraction · 2 oz

This handcrafted extract of Peganum harmala (Syrian rue) is a traditional potentiator revered for its MAO-inhibiting and psychoactive properties. Carefully crafted using a dual-extraction process with organic cane alcohol, organic glycerin, and spring water, this formulation preserves a broad spectrum of active alkaloids and delivers them in a bioavailable format.

Key Compounds

The seeds of Peganum harmala are rich in harmala alkaloids, primarily harmine, harmaline, and tetrahydroharmine—beta-carbolines also found in Banisteriopsis caapi, the vine of the Amazonian brew ayahuasca. These compounds act as reversible MAO-A inhibitors (RIMAs), allowing for the oral activity of certain otherwise-inactive compounds like DMT and enhancing the effects of entheogens such as psilocybin, mescaline, and 5-MeO-DMT.

Other naturally occurring alkaloids include:

• Harmalol

• Harmane

• Harmidine

• Norharmine

• Tetrahydroharmaline

Scientific Insight

Studies have shown that harmala alkaloids:

• Inhibit monoamine oxidase A (MAO-A), affecting neurotransmitter metabolism such as serotonin, dopamine, and melatonin

• Exhibit neuroprotective and antioxidant properties (Mol Pharmacol. 2008)

• May support mood regulation and induce altered states of consciousness when combined with other plant sacraments

(Note: This is not a recreational product. This extract is offered as a spiritual and ceremonial preparation aid.)