
Focus · Neuroplasticity · Mood · Cognitive
Stamets stack — Lions mane & niacin
The liquid form of our bestselling Lions Brain formula — the Stamets Stack in a fast-acting, highly bioavailable liquid extract.
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ABOUT THIS FORMULA
Lions Brain Liquid Extract delivers the same powerful Stamets Stack as our capsule formula — Lions Mane, Psilocybe cubensis, and Niacin — in a faster-acting, more bioavailable liquid form. The liquid is absorbed sublingually for rapid onset, making it ideal for acute cognitive support.
The Stamets Stack is named after mycologist Paul Stamets, who popularized this synergistic combination for neuroplasticity and cognitive enhancement. Lions Mane stimulates Nerve Growth Factor; the entheogenic mushroom amplifies neuroplasticity; Niacin drives the compounds deeper into the nervous system.
This is the same formula as our capsules, just in a more immediate form. Many customers keep both — capsules for their regular protocol and liquid for acute support when they need it most.
THE STAMETS STACK
Developed by mycologist Paul Stamets, the Stamets Stack is the most researched microdosing protocol in the world — combining three synergistic compounds to rewire the brain from the inside out.

CAPSULES · BEST SELLER
Lions Mane · Psilocybe cubensis · Niacin
25 capsules — 3–5×/week protocol
$72.22

LIQUID EXTRACT
Dual-extracted · Full-spectrum
Faster absorption · 2 oz dropper
$66.66
Lions Mane stimulates NGF production — a protein essential for the growth, maintenance, and survival of neurons. NGF literally rebuilds your brain.
The microdose of Psilocybe cubensis activates 5-HT2A receptors, dramatically amplifying neuroplasticity and making the brain more receptive to Lions Mane's NGF.
Niacin (Vitamin B3) causes a peripheral flush that drives the active compounds deeper into the nervous system — reaching areas that would otherwise be inaccessible.
Users report reduced anxiety, lifted depression, and greater emotional resilience. The stack supports serotonin pathways and default mode network regulation.
Improved memory, sharper focus, and faster processing. Studies show Lions Mane can reverse cognitive decline and support recovery from neurological damage.
Mycologist Paul Stamets — the world's leading mushroom researcher — developed this protocol after decades of research. He holds a patent on the combination.
"The combination of Lion's Mane, psilocybin, and niacin creates a synergistic effect that is greater than the sum of its parts — potentially offering a pathway to enhanced neurogenesis and cognitive repair."
— PAUL STAMETS, MYCOLOGIST & RESEARCHER
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